Maidenhead MP Theresa May has said she will stand for leadership of the Conservative Party.
The Home Secretary has confirmed she will stand in a letter in tomorrow's Times and will now stand a chance of becoming the next Prime Minister.
It comes after David Cameron announced he was resigning from the role after the UK voted to leave the European Union in Thursday's referendum.
Mrs May is the bookies' favourite to become leader, ahead of former Mayor of London and Leave campaigner Boris Johnson.
She sided with the Remain campaign during the EU referendum, during which both of her constituency's boroughs, Windsor and Maidenhead and Wokingham, voted with her.
She became MP for Maidenhead in 1997 and lives locally, often attending events in her constituency.
Recently, she has been involved in the Save Poundfield campaign in Cookham, a protest against plans to build on green space, and supported the efforts to improve Maidenhead town centre.
In 2015 she was elected with 35,453 votes - 29,059 more than the candidate with the second highest number of votes.
Between 1999 and 2010 she served in the Tory shadow cabinet, and was named Home Secretary when the Conservatives entered government after the General Election in May 2010.
After close of nominations on Thursday, MPs will select just two candidates to go before 150,000 Tory members who will decide the contest.
A final result is set to be declared on September 2.
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The Met Office has issued a yellow alert for Windsor and Maidenhead, Slough and Wokingham, warning that rain moving eastwards across the south of the country may turn to snow in some places.