Four men from Maidenhead have been arrested on suspicion of GBH in Reading.
They, and another man from Taunton in Somerset, were arrested following a fight in the Broad Street area early on Sunday morning which left a 24-year-old man seriously injured.
The man from Woosehill near Wokingham was taken to hospital and has been diagnosed with a bleed to the brain.
He remains under close observation.
The five men, all aged between 19 and 21, have been bailed to appear at Loddon Valley Police Station on April 22.
Witnesses have been urged to call police on 101.
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The crash, which took place at about 7am today (Thursday), involved three vehicles. One man sadly died as a result of the collision and his next of kin have been informed.