'Rabbits' will race through the town's streets on Sunday, March 4, as part of a new Charity Bunny Fun Run.
Entries are now open for men, women and children to enter the 5km race organised by the Rotary Club of Maidenhead Thames.
Participants are encouraged to dress up as bunnies to create a fun atmosphere and help welcome the advent of spring.
Kicking off at 9.30am, the race will start and end in Oaken Grove Park. The figure-of-eight route takes in streets in the Belmont Park and Halifax Road areas.
Early entrants will be provided with a free bunny outfit to wear and keep, including a T-shirt, ears and a short tail.
Should the event be a success it is hoped it will be held annually.
The club also hopes holding the inaugural fun run in the year of the London Olympics will encourage more people to take up running.
Some road closures will be required, and about 1,000 letters will be sent out to households on the route to make sure people are informed.
While the fun run is open to anyone of any ability, prizes will be awarded to the fastest runners.
Entry costs £14 for over 18s, £9 for those aged 12-18, £5 for children aged six to 12 and is free for children under six.
Half of each runner's sponsorship money will go to a charity of their choice and the rest to Rotary charities.
The event is sponsored by the Michael Shanly Charitable Trust.
Visit www.maidenheadthamesrotary.org for details.
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